Biochemical pharmacology · 2018 · Cell / animal study · PMID 29155147
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Preclinical evidenceSmall-molecule NNMT inhibitor; not a peptide
5-Amino-1MQ
5-Amino-1MQ is a synthetic small molecule studied as an inhibitor of the NNMT enzyme. It is included alongside peptides because of its metabolic-research context, but it is not a peptide.
Also indexed as: NNMT inhibitor
A clear starting point
5-Amino-1MQ is a synthetic small molecule studied as an inhibitor of the NNMT enzyme. It is included alongside peptides because of its metabolic-research context, but it is not a peptide.
Systems mapping shows biological relevance, not a treatment recommendation or a patient CPI score.
No validated chemical structure is displayed in this edition.
How it works
NNMT / cellular metabolism
5-Amino-1MQ is a synthetic small molecule studied as an inhibitor of the NNMT enzyme. It is included alongside peptides because of its metabolic-research context, but it is not a peptide.
- Targets & processes
- NNMT / cellular metabolism
- Systems & tissues
- See the pathway description; category links describe research relevance, not demonstrated treatment effects.
What does the evidence show?
Adipose metabolism and metabolic dysfunction in experimental models.
What this does not establish
The cited study examines diet-induced obesity in mice, not weight loss in people.
Citation metadata from PubMed, a service of the U.S. National Library of Medicine, NIH. A citation match is not a guarantee of study quality. Abstracts are not full-text reviews.
Safety is a separate question
Human toxicology, drug interactions and long-term risks are not established. Effects on methylation and NAD metabolism require further study.
Contraindications & cautions
Not an exhaustive contraindication review. Human toxicology, drug interactions and long-term risks are not established. Effects on methylation and NAD metabolism require further study.
Medication & supplement interactions
Interaction information is incomplete. Human toxicology, drug interactions and long-term risks are not established. Effects on methylation and NAD metabolism require further study.
Regulatory status · United States
Not FDA-approved. No FDA-approved finished drug for this molecule is identified in this edition. Investigational use, published research or compounding does not establish FDA approval.
This is not an exhaustive safety list. Regulatory status varies by jurisdiction and product; investigational use is not approval.
Make the science interactive
A dedicated lesson has not been published for this ingredient yet. Explore the cited profile or ask the instructor.
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Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.
Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.