Lancet (London, England) · 2021 · Clinical trial · PMID 34798060
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Limited human evidenceLong-acting amylin analog
Cagrilintide
Cagrilintide is a long-acting peptide analog of amylin, a hormone normally released alongside insulin. It is an investigational metabolic agent.
Also indexed as: Long-acting amylin analog
A clear starting point
Cagrilintide is a long-acting peptide analog of amylin, a hormone normally released alongside insulin. It is an investigational metabolic agent.
Systems mapping shows biological relevance, not a treatment recommendation or a patient CPI score.
No validated chemical structure is displayed in this edition.
How it works
Amylin signaling
Cagrilintide is a long-acting peptide analog of amylin, a hormone normally released alongside insulin. It is an investigational metabolic agent.
- Targets & processes
- Amylin signaling
- Systems & tissues
- See the pathway description; category links describe research relevance, not demonstrated treatment effects.
What does the evidence show?
Appetite regulation and body-weight outcomes in controlled studies.
What this does not establish
The cited dose-finding phase 2 trial does not establish approval or suitability for an individual.
Citation metadata from PubMed, a service of the U.S. National Library of Medicine, NIH. A citation match is not a guarantee of study quality. Abstracts are not full-text reviews.
Safety is a separate question
Nausea and other gastrointestinal effects occur in trials. Long-term safety and interactions outside studied protocols remain uncertain.
Contraindications & cautions
Not an exhaustive contraindication review. Nausea and other gastrointestinal effects occur in trials. Long-term safety and interactions outside studied protocols remain uncertain.
Medication & supplement interactions
Interaction information is incomplete. Nausea and other gastrointestinal effects occur in trials. Long-term safety and interactions outside studied protocols remain uncertain.
Regulatory status · United States
Not FDA-approved. No FDA-approved finished drug for this molecule is identified in this edition. Investigational use, published research or compounding does not establish FDA approval.
This is not an exhaustive safety list. Regulatory status varies by jurisdiction and product; investigational use is not approval.
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A dedicated lesson has not been published for this ingredient yet. Explore the cited profile or ask the instructor.
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Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.
Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.