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Insufficient evidenceNonselective melanocortin receptor agonist

Melanotan II

Melanotan II is a synthetic melanocortin analog associated with pigmentation and historical sexual-function research. It is not an FDA-approved tanning medication.

Also indexed as: MT-II

A clear starting point

Melanotan II is a synthetic melanocortin analog associated with pigmentation and historical sexual-function research. It is not an FDA-approved tanning medication.

Systems mapping shows biological relevance, not a treatment recommendation or a patient CPI score.

No validated chemical structure is displayed in this edition.

How it works

Melanocortin signaling

Melanotan II is a synthetic melanocortin analog associated with pigmentation and historical sexual-function research. It is not an FDA-approved tanning medication.

Targets & processes
Melanocortin signaling
Systems & tissues
See the pathway description; category links describe research relevance, not demonstrated treatment effects.

What does the evidence show?

Pigmentation and historical sexual-function research.

What this does not establish

The reference citation could not be independently matched in this edition. FDA safety information is linked; cosmetic efficacy and long-term safety are not established.

Citation metadata from PubMed, a service of the U.S. National Library of Medicine, NIH. A citation match is not a guarantee of study quality. Abstracts are not full-text reviews.

Safety is a separate question

Serious case reports include priapism, neurological syndromes and melanoma; case reports do not establish causality. Changes in skin lesions warrant medical evaluation. Tanning does not ensure UV protection.

Contraindications & cautions

Not an exhaustive contraindication review. Serious case reports include priapism, neurological syndromes and melanoma; case reports do not establish causality. Changes in skin lesions warrant medical evaluation. Tanning does not ensure UV protection.

Medication & supplement interactions

Interaction information is incomplete. Serious case reports include priapism, neurological syndromes and melanoma; case reports do not establish causality. Changes in skin lesions warrant medical evaluation. Tanning does not ensure UV protection.

Regulatory status · United States

Not FDA-approved. No FDA-approved finished drug for this molecule is identified in this edition. Investigational use, published research or compounding does not establish FDA approval.

Read the official source

This is not an exhaustive safety list. Regulatory status varies by jurisdiction and product; investigational use is not approval.

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A dedicated lesson has not been published for this ingredient yet. Explore the cited profile or ask the instructor.

View the preserved original research profile, glossary and reading trails

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Education, not a prescription. Research summaries are not medical advice, dosing instructions, or an offer to sell. Mechanistic findings do not establish clinical effectiveness. US regulatory status is product- and indication-specific and may change. Discuss health decisions with a licensed clinician.