Bioorganicheskaia khimiia · 2004 · Cell / animal study · PMID 15344653
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Insufficient evidenceSynthetic ACTH-fragment analog
Semax
Semax is a synthetic peptide analog related to an ACTH fragment. This profile covers research context without assuming that laboratory findings establish cognitive or neurological treatment benefit.
Also indexed as: ACTH 4-10 analog
A clear starting point
Semax is a synthetic peptide analog related to an ACTH fragment. This profile covers research context without assuming that laboratory findings establish cognitive or neurological treatment benefit.
Systems mapping shows biological relevance, not a treatment recommendation or a patient CPI score.
No validated chemical structure is displayed in this edition.
How it works
ACTH-related / neurotrophic signaling
Semax is a synthetic peptide analog related to an ACTH fragment. This profile covers research context without assuming that laboratory findings establish cognitive or neurological treatment benefit.
- Targets & processes
- ACTH-related / neurotrophic signaling
- Systems & tissues
- See the pathway description; category links describe research relevance, not demonstrated treatment effects.
What does the evidence show?
Neuropeptide signaling and neurological research hypotheses.
What this does not establish
The linked receptor-binding study uses rat brain membranes; it is not a human cognition trial. Regional clinical reports require independent replication and appraisal.
Citation metadata from PubMed, a service of the U.S. National Library of Medicine, NIH. A citation match is not a guarantee of study quality. Abstracts are not full-text reviews.
Safety is a separate question
FDA identifies limited safety information and possible immunogenicity and peptide impurities. Long-term neurological effects and drug interactions remain uncertain.
Contraindications & cautions
Not an exhaustive contraindication review. FDA identifies limited safety information and possible immunogenicity and peptide impurities. Long-term neurological effects and drug interactions remain uncertain.
Medication & supplement interactions
Interaction information is incomplete. FDA identifies limited safety information and possible immunogenicity and peptide impurities. Long-term neurological effects and drug interactions remain uncertain.
Regulatory status · United States
Not FDA-approved. No FDA-approved finished drug for this molecule is identified in this edition. Investigational use, published research or compounding does not establish FDA approval.
Read the official sourceThis is not an exhaustive safety list. Regulatory status varies by jurisdiction and product; investigational use is not approval.
Make the science interactive
A dedicated lesson has not been published for this ingredient yet. Explore the cited profile or ask the instructor.
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Basic level · Published sources only · AI evidence check
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All medications and therapies discussed are for educational purposes only. Prescriptions are determined independently by the licensed clinician following a medical evaluation. There is no guarantee that any medication or peptide will be prescribed.
IW Interactive Learning Engine · Adapted from stable OpenMAIC v1.2.1. Open-source license
Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.
Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.