GeroScience · 2024 · Journal Article; Systematic Review · PMID 37851316
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Limited human evidenceAmino acid / protein constituent
Glycine
Glycine is an amino acid found in proteins and studied for sleep-related effects. Small human sleep studies do not establish it as a treatment for insomnia or aging.
Also indexed as: Gly
A clear starting point
Glycine is an amino acid found in proteins and studied for sleep-related effects. Small human sleep studies do not establish it as a treatment for insomnia or aging.
Systems mapping shows biological relevance, not a treatment recommendation or a patient CPI score.
No validated chemical structure is displayed in this edition.
How it works
Protein biology / nervous-system research
Glycine is an amino acid found in proteins and studied for sleep-related effects. Small human sleep studies do not establish it as a treatment for insomnia or aging.
- Targets & processes
- Protein constituent and signaling-related amino acid; a single validated sleep-treatment target is not established here.
- Systems & tissues
- Protein synthesis and nervous-system research.
What does the evidence show?
Preliminary studies report sleep-related improvements, but the review highlights small samples and high risk of bias.
What this does not establish
Short studies and selected populations do not establish long-term efficacy, prevention of age-related disease or a substitute for sleep-disorder evaluation.
Citation metadata from PubMed, a service of the U.S. National Library of Medicine, NIH. A citation match is not a guarantee of study quality. Abstracts are not full-text reviews.
Safety is a separate question
The selected review does not provide a comprehensive long-term safety assessment. Protein occurrence does not establish safety of every supplemental use.
Contraindications & cautions
Pregnancy, breastfeeding and serious illness lack adequate evidence in this profile.
Medication & supplement interactions
Reliable supplement–medicine interaction data are incomplete; no blanket compatibility claim is possible.
Regulatory status · United States
United States: dietary-supplement status is product-specific, not FDA approval of disease treatment. Food, supplement and drug formulations must not be assumed interchangeable.
This is not an exhaustive safety list. Regulatory status varies by jurisdiction and product; investigational use is not approval.
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Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.
Education only. Confidence labels are not formal systematic evidence grades. No patient record is used.